{"id":16602,"date":"2015-09-02T23:47:27","date_gmt":"2015-09-02T13:47:27","guid":{"rendered":"https:\/\/intensivecarenetwork.com\/?p=16602"},"modified":"2015-09-27T12:53:34","modified_gmt":"2015-09-27T02:53:34","slug":"bloody-anticoagulants","status":"publish","type":"post","link":"https:\/\/intensivecarenetwork.com\/bloody-anticoagulants\/","title":{"rendered":"Bloody Anticoagulants"},"content":{"rendered":"<p>Bloody Oral Anticoagulants<br \/>\nCelia Bradford, \u2013 BCC 2014<\/p>\n<p>The use of the New Oral Anticoagulant Drugs present unique challenges for the Intensive Care practitioner<\/p>\n<p>1. The NOACs now have PBS approval for non-valvular AF, below knee DVT, DVT prophylaxis and low volume PE<\/p>\n<p>2. There is no specific antidote for NOAC related bleeding but don\u2019t despair there are some things that can help<\/p>\n<p>3. Routine coagulation testing does not reflect drug levels or anticoagulation activity<\/p>\n<p>Global sales of Dabigatran topped $1billion in 2012.<\/p>\n<p>This talk outlines the pharmacodynamics and pharmacokinetics of the NOACs. Limitations and cautions of use are outlined with a review of the extensive literature. Clinical cases involving the NOACs are presented. The timing of stopping the agents before minor or major surgery, the approach to a patient with intracranial haemorrhage taking oral anticoagulants and the challenges faced when patients have an Acute Kidney Injury whilst taking these<\/p>\n<p><iframe loading=\"lazy\" id=\"iframe_container\" src=\"https:\/\/prezi.com\/embed\/qd-is1c_bkqj\/?bgcolor=ffffff&amp;lock_to_path=0&amp;autoplay=0&amp;autohide_ctrls=0&amp;landing_data=bHVZZmNaNDBIWkRDVE93YVVDTVN5dWF2eDNlZVpKOWl2d1IwbGozbmpvdjFXSXo1TG91aWlHVjc0OHdERURtVFhSbUJEUT09&amp;landing_sign=7IRwuVWR0AutfotXOQ6i6AdNWYIdlbzhbiOo9HDmK6g\" width=\"1000\" height=\"600\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\"><\/iframe><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The use of the New Oral Anticoagulant Drugs present unique challenges for the Intensive Care practitioner<\/p>\n","protected":false},"author":8,"featured_media":16604,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_price":"","_stock":"","_tribe_ticket_header":"","_tribe_default_ticket_provider":"","_tribe_ticket_capacity":"0","_ticket_start_date":"","_ticket_end_date":"","_tribe_ticket_show_description":"","_tribe_ticket_show_not_going":false,"_tribe_ticket_use_global_stock":"","_tribe_ticket_global_stock_level":"","_global_stock_mode":"","_global_stock_cap":"","_tribe_rsvp_for_event":"","_tribe_ticket_going_count":"","_tribe_ticket_not_going_count":"","_tribe_tickets_list":[],"_tribe_ticket_has_attendee_info_fields":false},"categories":[128,110,109],"tags":[2569,2562,1217,2564,2567,2563,761,187,2570,2566,2565,2568,2560,2561],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v15.4 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Bloody Anticoagulants - Intensive Care Network<\/title>\n<meta name=\"description\" content=\"The use of the New Oral Anticoagulant Drugs present unique challenges for the Intensive Care practitioner\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/intensivecarenetwork.com\/bloody-anticoagulants\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Bloody Anticoagulants - Intensive Care Network\" \/>\n<meta property=\"og:description\" content=\"The use of the New Oral Anticoagulant Drugs present unique challenges for the Intensive Care practitioner\" \/>\n<meta property=\"og:url\" content=\"https:\/\/intensivecarenetwork.com\/bloody-anticoagulants\/\" \/>\n<meta property=\"og:site_name\" content=\"Intensive Care Network\" \/>\n<meta property=\"article:author\" content=\"https:\/\/www.facebook.com\/ojflower\" \/>\n<meta property=\"article:published_time\" content=\"2015-09-02T13:47:27+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2015-09-27T02:53:34+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/intensivecarenetwork.com\/wp-content\/uploads\/2015\/09\/09blood.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"2800\" \/>\n\t<meta property=\"og:image:height\" content=\"1000\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\">\n\t<meta name=\"twitter:data1\" content=\"Oliver Flower\">\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\">\n\t<meta name=\"twitter:data2\" content=\"1 minute\">\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Organization\",\"@id\":\"https:\/\/intensivecarenetwork.com\/#organization\",\"name\":\"Intensive Care Network\",\"url\":\"https:\/\/intensivecarenetwork.com\/\",\"sameAs\":[],\"logo\":{\"@type\":\"ImageObject\",\"@id\":\"https:\/\/intensivecarenetwork.com\/#logo\",\"inLanguage\":\"en-US\",\"url\":\"https:\/\/intensivecarenetwork.com\/wp-content\/uploads\/2015\/08\/ICN_LOGO_SQ_small_filled.jpg\",\"width\":1308,\"height\":1308,\"caption\":\"Intensive Care Network\"},\"image\":{\"@id\":\"https:\/\/intensivecarenetwork.com\/#logo\"}},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/intensivecarenetwork.com\/#website\",\"url\":\"https:\/\/intensivecarenetwork.com\/\",\"name\":\"Intensive Care Network\",\"description\":\"Critical Care Education and Connectivity\",\"publisher\":{\"@id\":\"https:\/\/intensivecarenetwork.com\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":\"https:\/\/intensivecarenetwork.com\/?s={search_term_string}\",\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"},{\"@type\":\"ImageObject\",\"@id\":\"https:\/\/intensivecarenetwork.com\/bloody-anticoagulants\/#primaryimage\",\"inLanguage\":\"en-US\",\"url\":\"https:\/\/intensivecarenetwork.com\/wp-content\/uploads\/2015\/09\/09blood.jpg\",\"width\":2800,\"height\":1000},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/intensivecarenetwork.com\/bloody-anticoagulants\/#webpage\",\"url\":\"https:\/\/intensivecarenetwork.com\/bloody-anticoagulants\/\",\"name\":\"Bloody Anticoagulants - 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He convenes the SMACC conference with Harris and Nickson, heads up the Intensive Care Network site and is into Neuro Crit Care, FOAMed, graphic design, martial arts and family life.\",\"sameAs\":[\"https:\/\/www.facebook.com\/ojflower\",\"https:\/\/twitter.com\/oliflower\"]}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","_links":{"self":[{"href":"https:\/\/intensivecarenetwork.com\/wp-json\/wp\/v2\/posts\/16602"}],"collection":[{"href":"https:\/\/intensivecarenetwork.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/intensivecarenetwork.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/intensivecarenetwork.com\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/intensivecarenetwork.com\/wp-json\/wp\/v2\/comments?post=16602"}],"version-history":[{"count":0,"href":"https:\/\/intensivecarenetwork.com\/wp-json\/wp\/v2\/posts\/16602\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/intensivecarenetwork.com\/wp-json\/wp\/v2\/media\/16604"}],"wp:attachment":[{"href":"https:\/\/intensivecarenetwork.com\/wp-json\/wp\/v2\/media?parent=16602"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/intensivecarenetwork.com\/wp-json\/wp\/v2\/categories?post=16602"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/intensivecarenetwork.com\/wp-json\/wp\/v2\/tags?post=16602"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}