92. TBI – ICU Management (2/2)

Matthew MacPartlin wraps up his TBI series by talking about prognostication as well as ICU management of neuroprophylaxis and seizure prophylaxis.

References for this talk

BTF Guidelines for the Management of Severe Traumatic Brain Injury, 3rd edition

A randomized, double-blind study of phenytoin for the prevention of post traumatic seizures. NEJM, 1990. Aug 23. 23:323(8): 497-502. 

PROTECT-III trial

EPO-TBI trial

EAST guidelines on stress ulcer prophylaxis

Early indicators of prognosis in severe TBI.. BTF guidelines 2007.

Predicting outcome after traumatic brain injury: practical prognostic models based on large cohort of international patients. MRC CRASH Trial Collaborators. BMJ 2008;336:425

MRC CRASH based TBI prognosis calculator

Validation of the MRC CRASH based TBI prognosis calculator – Predicting outcome after traumatic brain injury: practical prognostic models based on large cohort of international patients. MRC CRASH Trial Collaborators. BMJ 2008;336:425 (Full text)

CRASH-II trial-based TBI prognosis calculator

Predicting early death in patients with traumatic bleeding: development and validation of prognostic model. Pablo Perel, David Prieto-Merino, Haleema Shakur, Tim Clayton, Fiona Lecky, Omar Bouamra, Rob Russell, Mark Faulkner, Ewout W Steyerberg, Ian Roberts. BMJ 2012;345:e5166

THE AUDIO

THE VIDEO

ICU management of TBI – Part II