Rupert Pearse talks to JICS Cast (James Day and Segun Olusanya) about how we can improving perioperative management of patients and the very interesting results from the OPTIMISE trial.
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- Pearse RM, Harrison DA, MacDonald N, Gillies MA, Blunt M, Ackland G, Grocott MPW, Ahern A, Griggs K, Scott R, Hinds C, Rowan K. Effect of a Perioperative, Cardiac Output-Guided Hemodynamic Therapy Algorithm On outcomes Following Major Gastrointestinal Surgery- A Randomized Clinical Trial and Systematic Review. JAMA 2014 (online first currently) May 19, 2014. http://jama.jamanetwork.com/article.aspx?articleid=1873985 . See the ESICM 2013 presentation here http://www.esicm.org/news-article/lives2013hottopics
- Grocott MPW, Pearse RM. Perioperative Medicine: The future of anaesthesia? BJA 108, 5: 723-726 (free full text at http://bja.oxfordjournals.org/content/108/5/723.long )
- Shoemaker WC, Appel PL, Kram HB, Waxman K, Lee TS. Prospective trial of supranormal values of survivors as therapeutic goals in high-risk surgical patients. Chest 1998: 94: 1176-86 (free full text at http://journal.publications.chestnet.org/data/Journals/CHEST/21586/1176.pdf )
- Gattinoni L, Brazzi L, Pelosi P, Latini R, Tognoni G, Pesenti A, Fumagalli R. A trial of Goal-Oriented Hemodynamic Therapy in Critically Ill patients. NEJM 1995; 333: 1025-1032 (free full text at http://www.nejm.org/doi/full/10.1056/NEJM199510193331601#t=article )
- All in a lather over TTM. http://lifeinthefastlane.com/all-in-a-lather-over-ttm/ (Last accessed 23/05/2014)
- Perner A et al. Hydroxyethyl Starch 130/0.42 versus Ringer’s Acetate in Severe Sepsis. NEJM 2012; 367: 124-134 (free full text at http://www.nejm.org/doi/full/10.1056/NEJMoa1204242#t=article )
- Myburgh JA et al. Hydroxyethyl Starch or Saline for Fluid Resuscitation in intensive Care. NEJM 2012; 367: 1901-1911 (free full text at http://www.nejm.org/doi/full/10.1056/NEJMoa1209759#t=article )
- Gillies MA, Habicher M, Jhanji S, Sander M, Mythen M, Hamilton M, Pearse RM. Incidence of postoperative death and acute kidney injury associated with IV 6% hydroxyethyl starch use: Systematic review and meta-analysis. BJA 112, 1: 25-34 (available online at http://bja.oxfordjournals.org/content/112/1/25.long- subscription only. Contact us for a copy)
